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A large-scale pilot clinical trial has been conducted by a network of trainee anaesthetists across the South West for the first time, thanks to support from the South West Anaesthesia Research Matrix (SWARM) and PenCLAHRC.
The trial was designed to assess whether a comprehensive oral hygiene regime could decrease the risk of post-operative pneumonia for patients undergoing major elective abdominal surgery.
Funded by an NIAA grant, the randomised control trial ‘CUPPA’ (Comprehensive moUth care and Post-operative PneumoniA) was delivered across six NHS hospital sites by more than 45 trainee clinicians specialising in anaesthesia, all members of the SWARM collaboration.
Data collection and analysis...Read more
The University of Exeter Medical School is seeking a Trial Manager to take a lead role in implementing the South West hub of an NIHR HTA funded trial.
The trial aims to evaluate the clinical and cost-effectiveness of a home-based exercise intervention as extended rehabilitation for frail older people after acute illness or injury (HERO). Building on successful previous work, a multi-site individually randomised controlled trial with internal pilot and embedded process evaluation is planned.
The Trial Manager will oversee the start-up and management of participating centres in the South West, working alongside Dr Vicki Goodwin (South West hub lead), the training team...Read more