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Staff Profile

Prof Christopher Hyde

Theme Lead for Diagnostics and Stratified Medicine

Kath Maguire

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Areas of expertise
Public Health, Clinical Epidemiology

Projects

Cardiac Reviews of Tests and Training (CaRoTT)

Using pharmacogenetics testing to identify monogenic diabetes earlier (The UNITED project)

Cancer Diagnostics Programme

UNTEST

Publications

Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia

Infliximab for the treatment of acute exacerbations of ulcerative colitis

Red cell transfusion for the management of upper gastrointestinal haemorrhage

A systematic review of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

Where are the systematic reviews in transfusion medicine? A Study of the transfusion evidence base

Clinical effectiveness and cost-effectiveness of stem cell transplantation in the management of acute leukaemia: a systematic review

Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: A systematic review and meta-analysis

The clinical effects of red blood cell transfusions: an overview of the randomized controlled trials evidence base

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Trauma-induced coagulopathy - a review of the systematic reviews: is there sufficient evidence to guide clinical transfusion practice?

The acute management of trauma hemorrhage: a systematic review of randomized controlled trials

An economic evaluation of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

A capture-recapture analysis demonstrated that randomized controlled trials evaluating the impact of diagnostic tests on patient outcomes are rare

Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer

Teaching critical appraisal skills in healthcare settings

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Community programs for the prevention of cardiovascular disease: a systematic review

The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes

Assessing the value of diagnostic tests: a framework for designing and evaluating trials

Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: systematic review and economic model

Diagnostic accuracy of single baseline measurement of Elecsys Troponin T high-sensitive assay for diagnosis of acute myocardial infarction in emergency department: systematic review and meta-analysis

Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis

Thromboelastography (TEG) and thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding

Improving screening recall services for women with false-positive mammograms: a comparison of qualitative evidence with UK guidelines

Tests for screening for hearing loss in children about to start school (Protocol)

A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children

A qualitative study into the difficulties experienced by healthcare decision makers when reading a Cochrane diagnostic test accuracy review

Variability in thyroid function test requests across general practices in South-west England

Methods to elicit probability distributions from experts: a review of reported practice in health technology assessment.

A crisis of visibility: the psychological consequences of false-positive screening mammograms, an interview study

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

A comparison of two methods for expert elicitation in health technology assessments

Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients

Psychological consequences of false-positive screening

Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

Effectiveness of interventions to reduce ordering of thyroid function tests: A systematic review

Exploring reasons for variation in ordering thyroid function tests in primary care: a qualitative study

Upcoming Events

Sep
06

Making Sense of Health Research...

Room 1.24 South Cloisters - University of Exeter - St Lukes Campus

An introduction to making sense of evidence Introduction to Making Sense of Evidence During this talk a...
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Sep
08

Frailty: Recent clinical advances and...

South Cloisters 3.06 (St Lukes Campus - University of Exeter)

PenCLAHRC/Complex Intervention Research Group Seminar Frailty: Recent clinical advances and next steps for research Friday 8th September...
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Calendar

News

Stroke Association awards funding for stroke thrombectomy collaboration

16 August 2017

A study into a new and more effective treatment for acute stroke in England, carried...
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Job opportunity - Graduate Research Assistant

14 August 2017

We are looking to recruit a part-time Graduate Research Assistant to support the work of Dr Vicki...
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Volunteers required for Singing with Aphasia study

02 August 2017

A PenCLAHRC trial team are looking for volunteers to help study the benefits of singing...
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News

Research Projects

PenCHORD - Optimising plastic surgery clinic scheduling at Derriford Hospital

Theme: Diagnostics & Stratified Medicine

This project would seek to assess how changing the length of clinic slots and /...
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Public involvement in suicide prevention

Theme: Mental Health & Dementia

A research programme examining a public health intervention designed to help members of the public...
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Research Projects