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Staff Profile

Prof Christopher Hyde

Theme Lead for Diagnostics and Stratified Medicine

Kath Maguire

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Areas of expertise
Public Health, Clinical Epidemiology

Projects

Cardiac Reviews of Tests and Training (CaRoTT)

Using pharmacogenetics testing to identify monogenic diabetes earlier (The UNITED project)

Cancer Diagnostics Programme

UNTEST

Publications

Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia

Infliximab for the treatment of acute exacerbations of ulcerative colitis

Red cell transfusion for the management of upper gastrointestinal haemorrhage

A systematic review of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

Where are the systematic reviews in transfusion medicine? A Study of the transfusion evidence base

Clinical effectiveness and cost-effectiveness of stem cell transplantation in the management of acute leukaemia: a systematic review

Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: A systematic review and meta-analysis

The clinical effects of red blood cell transfusions: an overview of the randomized controlled trials evidence base

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Trauma-induced coagulopathy - a review of the systematic reviews: is there sufficient evidence to guide clinical transfusion practice?

The acute management of trauma hemorrhage: a systematic review of randomized controlled trials

An economic evaluation of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

A capture-recapture analysis demonstrated that randomized controlled trials evaluating the impact of diagnostic tests on patient outcomes are rare

Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer

Teaching critical appraisal skills in healthcare settings

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Community programs for the prevention of cardiovascular disease: a systematic review

The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes

Assessing the value of diagnostic tests: a framework for designing and evaluating trials

Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: systematic review and economic model

Diagnostic accuracy of single baseline measurement of Elecsys Troponin T high-sensitive assay for diagnosis of acute myocardial infarction in emergency department: systematic review and meta-analysis

Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis

Thromboelastography (TEG) and thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding

Improving screening recall services for women with false-positive mammograms: a comparison of qualitative evidence with UK guidelines

Tests for screening for hearing loss in children about to start school (Protocol)

A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children

A qualitative study into the difficulties experienced by healthcare decision makers when reading a Cochrane diagnostic test accuracy review

Variability in thyroid function test requests across general practices in South-west England

Methods to elicit probability distributions from experts: a review of reported practice in health technology assessment.

A crisis of visibility: the psychological consequences of false-positive screening mammograms, an interview study

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

A comparison of two methods for expert elicitation in health technology assessments

The comparative diagnostic accuracy of the Mini Mental State Examination (MMSE) and the General Practitioner assessment of Cognition (GPCOG) for identifying dementia in primary care: A systematic review protocol.

Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients

Psychological consequences of false-positive screening

Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

Effectiveness of interventions to reduce ordering of thyroid function tests: A systematic review

Exploring reasons for variation in ordering thyroid function tests in primary care: a qualitative study

Upcoming Events

Feb
27

'Creating Engaging Oral Communications'

Exeter South Cloisters 3.06, Plymouth JBB MR8, Truro KSpa F1.

This seminar aims to explore how to create engaging oral presentations. Jointly delivered by Michelle Ryan from the...
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Mar
06

PPI Advice Clinic

The University of Exeter, St Luke's campus, South Cloisters

Patient and Public Involvement Clinic What? These clinics have been set up to help the PenCLAHRC PPI Team manage and respond...
More information

Calendar

News

Partner In Focus - South West Academic Health Science Network

17 January 2018

As a partnership of NHS Trusts across Devon, Cornwall and Somerset, plus the Universities of...
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Members of PenCHORD team makes switch to Open Source working

15 December 2017

Members of PenCLAHRC's operational research team, PenCHORD, have been working towards transferring their work to Free Open Source Software (FOSS). Dr...
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Using Implementation Science to drive health care change: The ASPIC project

14 December 2017

Understanding how to put effective health care into practice is an important part of the...
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News

Research Projects

What are the effects of 'robopets' on the health and wellbeing of residents in care homes? A systematic review of qualitative and quantitative evidence

Theme: Mental Health & Dementia

A systematic review that aims to create a state-of-knowledge synthesis on the impact of robopet-human...
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Supporting older people to manage their medicines: a scoping review of medicine self-management tools

Theme: Person-Centred Care

A scoping review that aims to identify what tools or resources are available for older...
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Research Projects