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Staff Profile

Prof Christopher Hyde

Theme Lead for Diagnostics and Stratified Medicine

Kath Maguire

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Areas of expertise
Public Health, Clinical Epidemiology

Projects

Cardiac Reviews of Tests and Training (CaRoTT)

UNTEST

Using pharmacogenetics testing to identify monogenic diabetes earlier (The UNITED project)

Cancer Diagnostics Programme

Publications

Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia

Infliximab for the treatment of acute exacerbations of ulcerative colitis

Red cell transfusion for the management of upper gastrointestinal haemorrhage

A systematic review of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

Where are the systematic reviews in transfusion medicine? A Study of the transfusion evidence base

Clinical effectiveness and cost-effectiveness of stem cell transplantation in the management of acute leukaemia: a systematic review

Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: A systematic review and meta-analysis

The clinical effects of red blood cell transfusions: an overview of the randomized controlled trials evidence base

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Trauma-induced coagulopathy - a review of the systematic reviews: is there sufficient evidence to guide clinical transfusion practice?

The acute management of trauma hemorrhage: a systematic review of randomized controlled trials

An economic evaluation of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

A capture-recapture analysis demonstrated that randomized controlled trials evaluating the impact of diagnostic tests on patient outcomes are rare

Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer

Teaching critical appraisal skills in healthcare settings

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Community programs for the prevention of cardiovascular disease: a systematic review

The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes

Assessing the value of diagnostic tests: a framework for designing and evaluating trials

Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: systematic review and economic model

Diagnostic accuracy of single baseline measurement of Elecsys Troponin T high-sensitive assay for diagnosis of acute myocardial infarction in emergency department: systematic review and meta-analysis

Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis

Thromboelastography (TEG) and thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding

Improving screening recall services for women with false-positive mammograms: a comparison of qualitative evidence with UK guidelines

Tests for screening for hearing loss in children about to start school (Protocol)

A qualitative study into the difficulties experienced by healthcare decision makers when reading a Cochrane diagnostic test accuracy review

Variability in thyroid function test requests across general practices in South-west England

Methods to elicit probability distributions from experts: a review of reported practice in health technology assessment.

A crisis of visibility: the psychological consequences of false-positive screening mammograms, an interview study

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

A comparison of two methods for expert elicitation in health technology assessments

Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients

Psychological consequences of false-positive screening

Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature

Effectiveness of interventions to reduce ordering of thyroid function tests: A systematic review

Exploring reasons for variation in ordering thyroid function tests in primary care: a qualitative study

Upcoming Events

Mar
30

PenCLAHRC Health Service Modelling Associates...

G18 Medical School Building - St Lukes Campus - Exeter EX1 1TE

This event is being arranged by the PenCHORD team to showcase the work of the...
More information

Apr
05

PPI Advice Clinic

Plymouth, ITTC Building (PL6 8BX)

Whatever your query, from finding out more about Patient and Public Involvement to creating a PPI...
More information

Calendar

News

£2 million grant to improve rehabilitation of older people after discharge from hospital

24 March 2017

A team of researchers specialising in care for older people, including PenCLAHRC Senior Research Fellow Dr Vicki Goodwin,...
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Impact of wobbly bridges and sky-scrapers on human health to be tested in new government-funded research centre

21 March 2017

The impact of vibrations from very tall buildings, wobbly bridges and floors on people’s health...
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Outcome of research prioritisation round 2016/17

20 March 2017

The research prioritisation process has been running since PenCLAHRC first formed in 2008 and is...
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News

Research Projects

PenCHORD: Streamlining Pre-operative Assessments at Royal Cornwall Hospitals NHS Trust

Theme: Evidence for Policy and Practice

Developing a simulation model of the potential impact of new NICE guidelines on pre-operative assessment...
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Research Projects