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Staff Profile

Prof Christopher Hyde

Theme Lead for Diagnostics and Stratified Medicine

Kath Maguire

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Areas of expertise
Public Health, Clinical Epidemiology

Projects

Cardiac Reviews of Tests and Training (CaRoTT)

Cancer Diagnostics Programme

Effectiveness of interventions to reduce ordering of thyroid function tests: a systematic review

UNTEST

Using pharmacogenetics testing to identify monogenic diabetes earlier (The UNITED project)

Publications

Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia

Infliximab for the treatment of acute exacerbations of ulcerative colitis

Red cell transfusion for the management of upper gastrointestinal haemorrhage

A systematic review of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

Where are the systematic reviews in transfusion medicine? A Study of the transfusion evidence base

Clinical effectiveness and cost-effectiveness of stem cell transplantation in the management of acute leukaemia: a systematic review

Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: A systematic review and meta-analysis

The clinical effects of red blood cell transfusions: an overview of the randomized controlled trials evidence base

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Trauma-induced coagulopathy - a review of the systematic reviews: is there sufficient evidence to guide clinical transfusion practice?

The acute management of trauma hemorrhage: a systematic review of randomized controlled trials

An economic evaluation of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

A capture-recapture analysis demonstrated that randomized controlled trials evaluating the impact of diagnostic tests on patient outcomes are rare

Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer

Teaching critical appraisal skills in healthcare settings

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Community programs for the prevention of cardiovascular disease: a systematic review

The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes

Assessing the value of diagnostic tests: a framework for designing and evaluating trials

Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: systematic review and economic model

Diagnostic accuracy of single baseline measurement of Elecsys Troponin T high-sensitive assay for diagnosis of acute myocardial infarction in emergency department: systematic review and meta-analysis

Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis

Thromboelastography (TEG) and thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding

Improving screening recall services for women with false-positive mammograms: a comparison of qualitative evidence with UK guidelines

Tests for screening for hearing loss in children about to start school (Protocol)

A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children

A qualitative study into the difficulties experienced by healthcare decision makers when reading a Cochrane diagnostic test accuracy review

Variability in thyroid function test requests across general practices in South-west England

Methods to elicit probability distributions from experts: a review of reported practice in health technology assessment.

A crisis of visibility: the psychological consequences of false-positive screening mammograms, an interview study

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

A comparison of two methods for expert elicitation in health technology assessments

EXPLICIT: a feasibility study of remote expert elicitation in health technology assessment

Systematic review of health economic impact evaluations of risk prediction models: stop developing, start evaluating

The comparative diagnostic accuracy of the Mini Mental State Examination (MMSE) and the General Practitioner assessment of Cognition (GPCOG) for identifying dementia in primary care: A systematic review protocol.

A methodology review on the incremental prognostic value of computed tomography biomarkers in addition to Framingham risk score in predicting cardiovascular disease: the use of association, discrimination and reclassification

Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients

Psychological consequences of false-positive screening

Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

First do no harm: pain relief for the peripheral venous cannulation of adults, a systematic review and network meta-analysis

Effectiveness of interventions to reduce ordering of thyroid function tests: A systematic review

Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study

Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study

Exploring reasons for variation in ordering thyroid function tests in primary care: a qualitative study

Upcoming Events

Oct
30

Searching and Review Clinic

Room 1.47, South Cloisters, St Luke's Campus, University of Exeter

These clinics have been set up to help the PenCLAHRC Evidence Synthesis Team to manage and respond...
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Nov
06

PPI Advice Clinics

Exeter (South Cloisters, St Luke’s)

Do you need to involve service users in your work? Whatever your query, from finding out...
More information

Calendar

News

Research shows weight loss can be boosted fivefold thanks to novel mental imagery technique

24 September 2018

Overweight people who used a new motivational intervention called Functional Imagery Training (FIT) lost an...
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PenCHORD teach at international summer school focused on economic modelling in healthcare

20 September 2018

This August saw the first International Summer School Riga (ISSR), which was hosted and organised...
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Stroke doubles dementia risk, concludes large-scale study

31 August 2018

People who have had a stroke are around twice as likely to develop dementia, according...
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News

Research Projects

D-PACT: Dementia - Person Aligned Care Team

Theme: Mental Health & Dementia

The Dementia – PACT (D-PACT) programme is a five-year project, funded by a National Institute...
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PenCHORD - Optimising the location of urgent care sites in Cornwall

Theme: PenCHORD

This project aimed to assess the optimal number and location of sites for patients to...
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Research Projects