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Staff Profile

Prof Christopher Hyde

Theme Lead for Diagnostics and Stratified Medicine

Kath Maguire

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Areas of expertise
Public Health, Clinical Epidemiology

Projects

Cardiac Reviews of Tests and Training (CaRoTT)

Cancer Diagnostics Programme

Effectiveness of interventions to reduce ordering of thyroid function tests: a systematic review

UNTEST

Using pharmacogenetics testing to identify monogenic diabetes earlier (The UNITED project)

Publications

Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia

Infliximab for the treatment of acute exacerbations of ulcerative colitis

Red cell transfusion for the management of upper gastrointestinal haemorrhage

A systematic review of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

Where are the systematic reviews in transfusion medicine? A Study of the transfusion evidence base

Clinical effectiveness and cost-effectiveness of stem cell transplantation in the management of acute leukaemia: a systematic review

Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: A systematic review and meta-analysis

The clinical effects of red blood cell transfusions: an overview of the randomized controlled trials evidence base

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Trauma-induced coagulopathy - a review of the systematic reviews: is there sufficient evidence to guide clinical transfusion practice?

The acute management of trauma hemorrhage: a systematic review of randomized controlled trials

An economic evaluation of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

A capture-recapture analysis demonstrated that randomized controlled trials evaluating the impact of diagnostic tests on patient outcomes are rare

Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer

Teaching critical appraisal skills in healthcare settings

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia

Community programs for the prevention of cardiovascular disease: a systematic review

The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes

Assessing the value of diagnostic tests: a framework for designing and evaluating trials

Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: systematic review and economic model

Diagnostic accuracy of single baseline measurement of Elecsys Troponin T high-sensitive assay for diagnosis of acute myocardial infarction in emergency department: systematic review and meta-analysis

Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis

Thromboelastography (TEG) and thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding

Improving screening recall services for women with false-positive mammograms: a comparison of qualitative evidence with UK guidelines

Tests for screening for hearing loss in children about to start school (Protocol)

A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children

A qualitative study into the difficulties experienced by healthcare decision makers when reading a Cochrane diagnostic test accuracy review

Variability in thyroid function test requests across general practices in South-west England

Methods to elicit probability distributions from experts: a review of reported practice in health technology assessment.

A crisis of visibility: the psychological consequences of false-positive screening mammograms, an interview study

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

A comparison of two methods for expert elicitation in health technology assessments

EXPLICIT: a feasibility study of remote expert elicitation in health technology assessment

Systematic review of health economic impact evaluations of risk prediction models: stop developing, start evaluating

The comparative diagnostic accuracy of the Mini Mental State Examination (MMSE) and the General Practitioner assessment of Cognition (GPCOG) for identifying dementia in primary care: A systematic review protocol.

A methodology review on the incremental prognostic value of computed tomography biomarkers in addition to Framingham risk score in predicting cardiovascular disease: the use of association, discrimination and reclassification

Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients

Psychological consequences of false-positive screening

Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

First do no harm: pain relief for the peripheral venous cannulation of adults, a systematic review and network meta-analysis

Effectiveness of interventions to reduce ordering of thyroid function tests: A systematic review

Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study

Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study

Exploring reasons for variation in ordering thyroid function tests in primary care: a qualitative study

Upcoming Events

Feb
26

Qualitative Research Advice Clinic for...

South Cloisters Room SC2.17, St Luke's Campus, University of Exeter

Whether you are a postgraduate student, academic or researcher, you can book an appointment to speak...
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Feb
27

HEE/NIHR Pre-doctoral Clinical Academic Fellowship...

Rolle 001, University of Plymouth Main Campus

A free workshop for any allied health professionals, nurses or midwives considering applying for a...
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Calendar

News

Home-based cardiac rehabilitation for heart failure improves quality of life

11 February 2019

Despite the proven effectiveness of cardiac rehabilitation programmes in reducing readmissions and risk of death...
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HSMA Presentation Seminar is a huge success

06 February 2019

Dr Daniel Chalk, PenCLAHRC’s Lead for the Health Services Modelling Associates (HSMA) Programme, considers the HSMA...
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Stroke patients to be admitted to hospitals with 24/7 specialist stroke care

24 January 2019

Stroke is a very serious medical emergency and expert care needs to be rapidly accessed...
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News

Research Projects

Social Prescribing - Cornwall and Plymouth Researcher in Residence

Theme: Healthy People, Healthy Environments

Evaluation work by a Researcher in Residence to assess implementation, reach, scope and acceptability of...
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ADAPT: Accelerated Design and Programme Testing

Theme: Evidence for Policy and Practice

The research involves adapting aspects of Family Nurse Partnership, an evidence-based programme for young mothers...
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Research Projects