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Staff Profile

Prof Ken Stein

Deputy Director of PenCLAHRC and Lead for Question Generation

Kath Maguire

I am Deputy Director of the PenCLAHRC, and in addition to involvement in a range of projects being carried out within PenCLAHRC, I have Executive responsibility for the PenCLAHRC Evidence Synthesis Team and the Peninsula Collaboration for Operational Research and Development (PenCHORD).

I graduated in Medicine from University of Bristol in 1987, then trained and worked as a general practitioner in Australia and Hampshire before specialising in public health medicine in Southampton. In 1999 I began work as a Consultant in Public Health Medicine at North and East Devon Health Authority, then Director of Public Health for Mid Devon Primary Care Trust. I combined this NHS work with academic work at the University of Exeter as founding Director of the Peninsula Technology Assessment Group (PenTAG), becoming a full time academic at Exeter in 2003. I was appointed to a Chair in Public Health in 2007.

Alongside my health services research within the University of Exeter, I have been involved in Health Technology Assessment (HTA) and development of national policy on the adoption of new treatments through NICE, where I was a member and vice chair of an Appraisal Committee for 15 years and remain part of their Scientific Advice Programme.  I have been involved in the National Institute for Health Research HTA programme since its early years in the 1990s and am Editor in Chief of the monograph series Health Technology Assessment, which puts almost all of the programme’s commissioned work into the public domain.  I’ve had a lot of experience in Evidence Synthesis through my work in HTA, the Cochrane Collaboration and PenCLAHRC’s Evidence Synthesis Team and was appointed as Director of the NIHR Systematic Review Programme in 2018.

 

 

 

 

Email me

Contact by phone
01392 726067

Employed by
University of Exeter

Areas of expertise
Public Health, Health Technology Assessment, Evidence Synthesis, Health Services Research

Projects

Non pharmacological interventions for Attention-Deficit/Hyperactivity Disorder (ADHD) delivered in school settings: a systematic review of quantitative and qualitative research

NICE Implementation

PenCHORD - Plymouth stroke visualisation

PenCHORD - Modelling rheumatology bottlenecks to facilitate patient-initiated clinics (PIC) rollout

Diabetic Footcare

Cardiac Reviews of Tests and Training (CaRoTT)

PenCHORD - Torbay Cardiology Clinic Scheduling

PenCHORD - Pathway modelling at Exeter Genito-Urinary Medicine (GUM) clinic

Community pharmacist home visits for elderly and/or vulnerable populations

Green Gym

Systematic review of patient-initiated clinics (PIC) in secondary care for people with chronic disease

Methods to synthesise evidence of implementation and knowledge translation

Effectiveness of mealtime interventions in elderly people living in residential care

Impact of Using Outdoor Spaces on the Physical and Mental Well-Being of Those With Dementia

Effectiveness of mindfulness-based stress reduction and mindfulness based cognitive therapy in vascular disease

Physical activity in outdoor natural environments vs physical activity indoors

Systematic review of patient initiated clinics (PICs) in patients with chronic or recurrent conditions managed in secondary care

The effectiveness of interventions to reduce acute paediatric hospital admissions

Implementation of falls prevention programmes

Antipsychotic prescribing in people with dementia resident in care homes

Falls

Group Singing for Aphasia

Effectiveness of TNFa inhibitors to reduce depression in chronic physical illness

Psychiatric disorders and emotional and behavioural disturbance in children excluded from school

Teacher-led interventions on social and emotional behaviour in primary school children

Telephone consultation follow-up following routine surgery

PenCHORD - Mapping and reconfiguration of hyperacute stroke services in Wales

PenCHORD - Maximising access to thrombectomy services for stroke in England

PenCHORD - The Zone Icebreak Personality Disorder Pathway Redesign

PenCHORD - Optimising plastic surgery clinic scheduling at Derriford Hospital

PenCHORD - North Devon Thrombolysis Pathway: Bottleneck Analysis

PenCHORD - Streamlining Pre-operative Assessments at Royal Cornwall Hospitals NHS Trust

PenCHORD - HepB: Optimising the management of chronic hepatitis B in children and young people

SW AHSN/PenCHORD project - Achieving step change in the emergency stroke pathway across the South West peninsula

PenCHORD - Fractured neck of femur: Fast track pathway modelling

PenCHORD - Modelling Radiographer-led discharge at Yeovil District Hospital

PenCHORD - Ophthalmology location analysis

PenCHORD - Determining the required size of a Clinical Decision Unit at Royal Devon & Exeter Hospital

PenCHORD: Modelling the optimal size of Derriford Ambulatory Care Unit (ACU)

PenCHORD - Chest Pain Diagnosis - Costs and Consequences

PenCHORD - SCN urgent care review: Modelling provision for stroke and cardiac services in the South West region

PenCHORD - Pathway mapping of STEP 2-4 psychological therapies in the NEW Devon area

PenCHORD - Integrating Muscular Skeletal therapy services in Cornwall

PenCHORD - DECODE: Modelling the impact of a dementia triage system on Exeter memory clinic waiting times

PenCHORD - QEIA tool validation and improvement

PenCHORD - Optimising Polypharmacy using Agent-Based Simulation

PenCHORD - TIA Clinic Mapping

PenCHORD - Scheduling Community Mental Health Assessment in Devon

PenCHORD - Redesigning Stroke Pathways at the Royal Devon & Exeter Hospital

PenCHORD - Quality impact in healthcare system change

PenCHORD - Optimising the location of outpatient services in Cornwall: Phase One

PenCHORD - A pilot of an out of hours telephony service for mental health enquiries

PenCHORD - Optimising GP Appointment Policies at Ivybridge Health Centre

PenCHORD - STEMI: Appropriate treatment for ST-elevation heart attacks

PenCHORD - Plymouth Community Nursing

PenCHORD - Neonatal

PenCHORD - Doctor First

PenCHORD - 18 week R2T

PenCHORD - A case study of Royal Devon & Exeter waste management process and practice

PenCHORD - Cornwall mental health service pathways

PenCHORD - Reducing A&E four hour breaches in Cornwall

PenCHORD - What are the factors that most influence demand for ambulances in South West England?

Non-pharmacological interventions for Attention-Deficit/Hyperactivity Disorder (ADHD) in school settings

PenCHORD - Streamlining the bladder cancer pathway at RCHT

PenCHORD - Cornwall acute and community stroke bed capacity modelling

PenCHORD - Torbay and South Devon stroke care

The Care Home Implementation and Knowledge Mobilisation Project (CHIK-P)

PenCHORD- Evaluation of the PenCHORD Health Service Modelling Associates programme (EmMA)

PenCHORD - Modelling high level health and social care capacity needs in Cornwall

PenCHORD - Optimising the location of urgent care sites in Cornwall

Supporting Teachers and Children in Schools (STARS)

Publications

Surgical procedures and non-surgical devices for the management of non-apnoeic snoring: a systematic review of clinical effects and associated treatment costs

NICE guidance on azacitidine for the treatment of myelodysplastic syndromes, chronic myelomonocytic leukaemia and acute myelomonocytic leukaemia

Cost-effectiveness of dasatinib and nilotinib for imatinib-resistant or -intolerant chronic phase chronic myeloid leukemia

Systematic review of the effectiveness and cost-effectiveness of bilateral multichannel cochlear implants in adults with severe-to-profound hearing loss

The precision of health state valuation by members of the general public using the standard gamble

Public health implications of establishing a national programme to screen young athletes in the UK

Do metronomes improve the quality of life in people with Parkinson's disease? A pragmatic, single-blind, randomized cross-over trial

Mind sharpeners for scientists: the EQUATOR Network

Adult Attention Deficit Hyperactivity Disorder (ADHD): public health implications

Effectiveness of multi-channel unilateral cochlear implants for profoundly deaf children: a systematic review

Sunitinib and bevacizumab for first line treatment of metastatic renal cell carcinoma: a systematic review and indirect comparison of clinical effectiveness

The effectiveness and cost-effectiveness of cochlear implants for severe to profound deafness in children and adults: a systematic review and economic model

Is combined resynchronisation and implantable defibrillator therapy a cost effective option for left ventricular dysfunction?

Maximising the population benefit from thrombolysis in acute ischemic stroke: a modeling study of in-hospital delays

Will delays in treatment jeopardize the population benefit from extending the time window for stroke thrombolysis?

The Potential of Operational Research

Involving patients in drug licensing decisions

Hyperacute stroke care and NHS England’s business plan

Cost-effectiveness of bevacizumab for diabetic macular oedema

The experience of heavy menstrual bleeding: A systematic review and meta-ethnography of qualitative studies

Can the retinal screening interval be safely increased to 2 years for Type 2 diabetic patients without retinopathy?

Does participating in physical activity in outdoor natural environments have a greater effect on physical and mental wellbeing than physical activity indoors? A systematic review

Patient initiated clinics for patients with chronic or recurrent conditions managed in secondary care: a systematic review of patient reported outcomes and patient and clinician satisfaction.

Effectiveness of mealtime interventions on behaviour symptoms of people with dementia living in care homes: A systematic review

Interventions to reduce inappropriate prescribing of antipsychotic medications in people with dementia resident in care homes: a systematic review

School exclusion in children with psychiatric disorder or impairing psychopathology: A systematic review

What Is the Impact of Using Outdoor Spaces Such as Gardens on the Physical and Mental Well-Being of Those With Dementia? A Systematic Review of Quantitative and Qualitative Evidence.

Cost effectiveness of collagen crosslinking for progressive keratoconus in the UK NHS

Maximizing the population benefit from thrombolysis in acute ischemic stroke: a modeling study of in-hospital delays

How lack of information hampers decision making in ophthalmology

Interventions to reduce acute paediatric hospital admissions: A systematic review

The effectiveness and cost-effectiveness of enzyme and substrate replacement therapies: a longitudinal cohort study of people with lysosomal storage disorders

Implementing the evidence for preventing falls among community-dwelling older people: a systematic review

Factors influencing the implementation of fall prevention programmes: a systematic review and synthesis of qualitative studies

Establishing local priorities for a health research agenda

Telephone consultations in place of face to face out-patient consultations for patients discharged from hospital following surgery: a systematic review

Methods to elicit probability distributions from experts: a review of reported practice in health technology assessment.

Evaluating the impact of a simulation study in emergency stroke care

Mental health related contact with education professionals in the British Child and Adolescent Mental Health Survey 2004

A comparison of two methods for expert elicitation in health technology assessments

Implementing simulation results in emergency stroke care

Prescribing of medication for attention deficit hyperactivity disorder among young people in the Clinical Practice Research Datalink 2005-2013: analysis of time to cessation

EXPLICIT: a feasibility study of remote expert elicitation in health technology assessment

The effect of teacher-led interventions on social and emotional behaviour in primary school children: a systematic review

Involving patients and the public in healthcare operational research - the challenges and opportunities

Effectiveness of mindfulness-based stress reduction and mindfulness based cognitive therapy in vascular disease: A systematic review and meta-analysis of randomised controlled trials

Creating psychological connections between intervention recipients: Development and focus group evaluation of a group singing session for people with aphasia

Patient initiated clinics for patients with chronic or recurrent conditions managed in secondary care: a systematic review of patient reported outcomes and patient and clinician satisfaction

Dissemination and implementation research in dementia care: a systematic scoping review and evidence map

Feasibility of a hyper-acute stroke unit model of care across England: a modelling analysis

An implementation science perspective on deprescribing

Patient involvement in drug licensing: a case study

Tumour necrosis factor α inhibitor therapy in chronic physical illness: a systematic review and meta-analysis of the effect on depression and anxiety

Meta-analyses of randomized controlled trials show suboptimal validity of surrogate outcomes for overall survival in advanced colorectal cancer

The experiences of and attitudes towards non-pharmacological interventions for attention deficit/hyperactivity disorder used in school settings: a systematic review and synthesis of qualitative research

Informing Reimbursement Decisions Using Cost-Effectiveness Modelling: A Guide to the Process of Generating Elicited Priors to Capture Model Uncertainties

A novel modelling and simulation capacity development initiative for the National Health Service

Enhancing the usability of systematic reviews by improving the consideration and description of interventions

Interventions to reduce acute paediatric hospital admissions: a systematic review

End-user involvement in a systematic review of quantitative and qualitative research of non-pharmacological interventions for attention deficit hyperactivity disorder (ADHD) delivered in school settings: reflections on the impacts and challenges.

A systematic review and synthesis of qualitative research: the influence of school context on symptoms of Attention Deficit Hyperactivity Disorder

Maximising access to thrombectomy services for stroke in England: A modelling study

Maximising access to thrombectomy services for stroke in England: A modelling study

Involving patients and the public in healthcare operational research

Non-pharmacological interventions for attention-deficit/hyperactivity disorder (ADHD) delivered in school settings: systematic reviews of quantitative and qualitative research

Upcoming Events

Jan
08

PPI Advice Clinic

Exeter (South Cloisters, St Luke’s)

Do you need to involve service users in your work? Whatever your query, from finding out...
More information

Feb
05

PPI Advice Clinic

Exeter (South Cloisters, St Luke’s)

Do you need to involve service users in your work? Whatever your query, from finding out...
More information

Calendar

News

Scheme to improve wellbeing of parent carers to start trials

04 December 2018

A support programme to help parents of disabled children stay healthy in mind and body...
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Partner in Focus: Torbay and South Devon NHS Foundation Trust

29 November 2018

As a partnership of NHS Trusts across Devon, Cornwall and Somerset, plus the Universities of...
Read more

The Patient Public Involvement team receive a visit from Norway

23 November 2018

PenCLAHRCs Patient Public Involvement (PPI) team got a visit from Norway, who were interested in learning...
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News

Research Projects

Early Learning Communities

Theme: Evidence for Policy and Practice

The research involves a review of the international evidence on how to promote the school...
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D-PACT: Dementia - Person Aligned Care Team

Theme: Mental Health & Dementia

The Dementia – PACT (D-PACT) programme is a five-year project, funded by a National Institute...
Read more

Research Projects