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Staff Profile

Prof William Henley

Professor of Medical Statistics

Kath Maguire

I joined PenCLAHRC in April 2010 as a senior statistician and have provided input into the design, development and execution of a range of projects. In 2012 I was appointed to a Chair in Medical Statistics at the University of Exeter Medical School where I currently lead the Health Statistics group. A particular focus of my research is developing and applying methods for making more effective use of routinely collected health data. I lead the MRC-funded Extending the Prior Event Rate Ratio (EPERR) project investigating quasi-experimental methods for addressing sources of bias when evaluating medical interventions using Primary Care databases. The outputs of this research could help to enhance decision making relating to planning of future randomised controlled trials, as well as guiding treatment options in the clinic.

Email me

Contact by phone
01392 726088

Employed by
University of Exeter

Areas of expertise
Statistics

Projects

Vitamin D and Cognitive Health: the DCog Project

Engager

Publications

National mortality rates from chronic liver disease and consumption of alcohol and pig meat

Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: a longitudinal study in pre-pubertal children (EarlyBird 17)

Predictors of extraordinary survival in the Iowa established populations for epidemiologic study of the elderly: cohort follow-up to 'Extinction'

Self-care in people with long term health problems: a community based survey

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

Hepatitis E virus coinfection in patients with HIV infection

Improved curve fits to summary survival data: application to economic evaluation of health technologies

Bisphenol A exposure is associated with in vivo estrogenic gene expression in adults

Congenital keratoconjunctivitis sicca and ichthyosiform dermatosis in 25 Cavalier King Charles spaniel dogs. Part I: clinical signs, histopathology, and inheritance

Urinary bisphenol a concentration and angiography-defined coronary artery stenosis

Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people

Toward a gene expression biomarker set for human biological age

Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06

The coronary artery disease-associated 9p21 variant and later life 20-year survival to cohort extinction

Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women

Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey

Fatness leads to inactivity, but inactivity does not lead to fatness: a longitudinal study in children (EarlyBird 45)

CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength

PMO-161?Hepatitis E (HEV) in South West England. Geographical, environmental and social factors: a case control study

Effectiveness of intervention on physical activity of children: systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54)

Leukocyte CCR2 expression is associated with mini-mental state examination (MMSE) score in older adults

Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults

The reliability and validity of the Everyday Feelings Questionnaire in a clinical population

Longer Lived Parents: Protective Associations With Cancer Incidence and Overall Mortality

The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with Lysosomal Storage Disorders

Long-term effectiveness of enzyme replacement therapy in adults with Gaucher disease: results from the NCS-LSD cohort study

Prior event rate ratio adjustment for hidden confounding in observational studies of treatment effectiveness: a pairwise Cox likelihood approach

An exercise intervention to prevent falls in people with Parkinson's disease: a pragmatic randomised controlled trial

The effectiveness and cost-effectiveness of enzyme and substrate replacement therapies: a longitudinal cohort study of people with lysosomal storage disorders

Can standardized diagnostic assessment be a useful adjunct to clinical assessment in child mental health services? A randomized controlled trial of disclosure of the Development and Well-Being Assessment to practitioners

The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with Lysosomal Storage Disorders

Vitamin D and the risk of dementia and Alzheimer disease

The Work and Social Adjustment Scale: Reliability, Sensitivity, and Value

Long-term effectiveness of enzyme replacement therapy in children with Gaucher disease: results from the NCS-LSD cohort study

What is the relationship between age and deprivation in influencing emergency hospital admissions? A model using data from a defined, comprehensive, all-age cohort in East Devon, UK

A repeated cross-sectional study examining the school impact on child weight status.

Vitamin D and Dementia

"The Work and Social Adjustment Scale: Reliability, Sensitivity, and Value"

(COCOA) Care for Offenders Continuity of Access

Systematic review and meta-analysis of the association between childhood overweight and obesity and primary school diet and physical activity policies

Effectiveness of enzyme replacement therapy in adults with late-onset Pompe disease: results from the NCS-LSD cohort study.

Long-term effectiveness of enzyme replacement therapy in Fabry disease: results from the NCS-LSD cohort study.

Association of Urinary Bisphenol A Concentration With Medical Disorders and Laboratory Abnormalities in Adults

Supporting Kids, avoiding Problems’ (SKIP), Relationships between school exclusion, psychopathology, development and attainment, a case control study

Variation in referral and access to new psychological therapy services by age: an empirical quantitative study

Mechanisms of action in mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) in people with physical and/or psychological conditions: A systematic review

Upcoming Events

Jan
29

Seminar on Open Access by...

South Cloisters 3.06, St Luke’s campus with video conferencing link to MR8, John Bull Building, Plymouth and F083 in Truro

  A life with no Windows. A 12 month exploration into living in an Open Science...
More information

Feb
06

PPI Advice Clinic

The University of Exeter, St Luke's campus, South Cloisters

Patient and Public Involvement Clinic What? These clinics have been set up to help the PenCLAHRC PPI Team manage and respond...
More information

Calendar

News

Partner In Focus - South West Academic Health Science Network

17 January 2018

As a partnership of NHS Trusts across Devon, Cornwall and Somerset, plus the Universities of...
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Members of PenCHORD team makes switch to Open Source working

15 December 2017

Members of PenCLAHRC's operational research team, PenCHORD, have been working towards transferring their work to Free Open Source Software (FOSS). Dr...
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Using Implementation Science to drive health care change: The ASPIC project

14 December 2017

Understanding how to put effective health care into practice is an important part of the...
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News

Research Projects

Parent-to-Parent Support Interventions for Parents of Babies Cared for in a Neonatal unit (PaReNt)

Theme: Mental Health & Dementia

A systematic review of qualitative and quantitative evidence of parent to parent support interventions for...
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Improving the Experience of Care for People with Dementia in Hospital (ACEDEM)

Theme: Mental Health & Dementia

Can we improve the experience of care for people with dementia in hospital? A synthesis...
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Research Projects