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Staff Profile

Prof William Henley

Professor of Medical Statistics

Kath Maguire

I joined PenCLAHRC in April 2010 as a senior statistician and have provided input into the design, development and execution of a range of projects. In 2012 I was appointed to a Chair in Medical Statistics at the University of Exeter Medical School where I currently lead the Health Statistics group. A particular focus of my research is developing and applying methods for making more effective use of routinely collected health data. I lead the MRC-funded Extending the Prior Event Rate Ratio (EPERR) project investigating quasi-experimental methods for addressing sources of bias when evaluating medical interventions using Primary Care databases. The outputs of this research could help to enhance decision making relating to planning of future randomised controlled trials, as well as guiding treatment options in the clinic.

Email me

Contact by phone
01392 726088

Employed by
University of Exeter

Areas of expertise
Statistics

Projects

Vitamin D and Cognitive Health: the DCog Project

Engager

Publications

National mortality rates from chronic liver disease and consumption of alcohol and pig meat

Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: a longitudinal study in pre-pubertal children (EarlyBird 17)

Predictors of extraordinary survival in the Iowa established populations for epidemiologic study of the elderly: cohort follow-up to 'Extinction'

Self-care in people with long term health problems: a community based survey

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

Hepatitis E virus coinfection in patients with HIV infection

Improved curve fits to summary survival data: application to economic evaluation of health technologies

Bisphenol A exposure is associated with in vivo estrogenic gene expression in adults

Congenital keratoconjunctivitis sicca and ichthyosiform dermatosis in 25 Cavalier King Charles spaniel dogs. Part I: clinical signs, histopathology, and inheritance

Urinary bisphenol a concentration and angiography-defined coronary artery stenosis

Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people

Toward a gene expression biomarker set for human biological age

Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06

The coronary artery disease-associated 9p21 variant and later life 20-year survival to cohort extinction

Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women

Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey

Fatness leads to inactivity, but inactivity does not lead to fatness: a longitudinal study in children (EarlyBird 45)

CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength

PMO-161?Hepatitis E (HEV) in South West England. Geographical, environmental and social factors: a case control study

Effectiveness of intervention on physical activity of children: systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54)

Leukocyte CCR2 expression is associated with mini-mental state examination (MMSE) score in older adults

Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults

The reliability and validity of the Everyday Feelings Questionnaire in a clinical population

Longer Lived Parents: Protective Associations With Cancer Incidence and Overall Mortality

The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with Lysosomal Storage Disorders

Long-term effectiveness of enzyme replacement therapy in adults with Gaucher disease: results from the NCS-LSD cohort study

Prior event rate ratio adjustment for hidden confounding in observational studies of treatment effectiveness: a pairwise Cox likelihood approach

An exercise intervention to prevent falls in people with Parkinson's disease: a pragmatic randomised controlled trial

The effectiveness and cost-effectiveness of enzyme and substrate replacement therapies: a longitudinal cohort study of people with lysosomal storage disorders

Can standardized diagnostic assessment be a useful adjunct to clinical assessment in child mental health services? A randomized controlled trial of disclosure of the Development and Well-Being Assessment to practitioners

The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with Lysosomal Storage Disorders

Vitamin D and the risk of dementia and Alzheimer disease

The Work and Social Adjustment Scale: Reliability, Sensitivity, and Value

Long-term effectiveness of enzyme replacement therapy in children with Gaucher disease: results from the NCS-LSD cohort study

What is the relationship between age and deprivation in influencing emergency hospital admissions? A model using data from a defined, comprehensive, all-age cohort in East Devon, UK

A repeated cross-sectional study examining the school impact on child weight status.

Vitamin D and Dementia

"The Work and Social Adjustment Scale: Reliability, Sensitivity, and Value"

(COCOA) Care for Offenders Continuity of Access

Systematic review and meta-analysis of the association between childhood overweight and obesity and primary school diet and physical activity policies

Effectiveness of enzyme replacement therapy in adults with late-onset Pompe disease: results from the NCS-LSD cohort study.

Long-term effectiveness of enzyme replacement therapy in Fabry disease: results from the NCS-LSD cohort study.

Association of Urinary Bisphenol A Concentration With Medical Disorders and Laboratory Abnormalities in Adults

Supporting Kids, avoiding Problems’ (SKIP), Relationships between school exclusion, psychopathology, development and attainment, a case control study

Variation in referral and access to new psychological therapy services by age: an empirical quantitative study

Mechanisms of action in mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) in people with physical and/or psychological conditions: A systematic review

The relationship between exclusion from school and mental health: a secondary analysis of the British Child and Adolescent Mental Health Surveys 2004 and 2007

Upcoming Events

Sep
27

Searching and Review Clinic

Room N14, ITTC Building, Plymouth

These clinics have been set up to help the PenCLAHRC Evidence Synthesis Team to manage and respond...
More information

Nov
16

Making Sense of Health Research...

Buckfast Abbey

  SAVE THE DATE Making Sense of Health Research Annual Conference 16th November 2018 You are invited to attend...
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Calendar

News

The NHS turns 70: Celebrating public involvement in health research

05 July 2018

On Thursday 5th July 2018, the NHS turned 70 years old. Since its inception, the NHS has constantly...
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Job Opportunity – PenCLAHRC Events and Training Coordinator

28 June 2018

The University of Exeter Medical School are looking to recruit an Events and Training Coordinator within...
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Clinician-led research to inform new guidance for therapists

26 June 2018

The results of a clinician-led study will inform a new evidence based guide for therapists...
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News

Research Projects

UNTEST

Theme: Diagnostics & Stratified Medicine

How can we help GPs make better use of thyroid function tests?
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Sharing Evidence Routine for a Patient Centred Plan of Action (SHERPA)

Theme: Person-Centred Care

This project aims to offer a structured approach for GP trainees to manage consultations with...
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Research Projects