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Staff Profile

Harriet Hunt

Research Fellow

Kath Maguire

I am a Research Fellow in Evidence Synthesis and Test Evaluation within the Institute of Health Research at the University of Exeter Medical School.
I’m particularly interested in how test information is understood. Working alongside Professor Chris Hyde has provided an education in test evaluation and associated knotty issues.  Through PenCLAHRC we have a network of highly expert researchers taking collaborative and cross-disciplinary approaches which allows test research to cut across the traditional topical and methods boundaries, working with groups including the Exeter Collaboration for Primary Care (APEx), Clinical Epidemiology, and the Cancer Diagnosis group (DISCO).

Dementia is a topical area with particular challenges for diagnostic testing in an environment where people often initially present to their general practitioner with concerns about their memory or cognitive performance. Investigating how to improve the current situation is the focus of my PhD research, with support from PenCLAHRC and collaboration with a range of other University of Exeter researchers. My principal supervisor is Professor Chris Hyde, and my co-supervisors are Dr Mark Pearson and Dr David Llewellyn.

I am also interested by the practical application of diagnostic test data. I teach part of the Clinical Decision Making course for our undergraduate medical students, and am keen to explore how ‘useable’ diagnostic information is for medics and non-medics, and how this usefulness might be improved. I am interested in the impact of false positive and false negative test results on the people who use this data, e.g. medical practitioners, patients and carers. Tests are used for various reasons such as screening, guiding therapy and predicting how a disease might progress. Prognosis is a developing area, and with Chris Hyde our investigations are also looking at the possible added prognostic value of some diagnostic tests.
At the moment, I am carrying out a doctoral research programme looking at optimizing cognitive assessment in primary care to support a more effective route to dementia diagnosis supported by PenCLAHRC. To find out more, please visit the PhD project page.
I have recently completed a Cochrane review of diagnostic test accuracy investigating Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma-induced coagulopathy in adult trauma patients with bleeding, published in the Cochrane Library and working with the Cochrane Injuries Group and colleagues at the University of Exeter, NIHR, Oxford Biomedical Research Centre, Oxford, John Radcliffe Hospital, NHS Blood & Transplant, Oxford, Churchill Hospital, Oxford Haemophilia & Thrombosis Centre, Oxford and the Royal Centre for Defence Medicine ICT Centre, Department of Military Anaesthesia and Critical Care, Birmingham.
I am also currently working with colleagues at John Radcliffe Hospital, NHS Blood & Transplant, Oxford, and the Department of Public Health and Primary Care, University of Cambridge on a diagnostic test accuracy review of tests of haemoglobin levels in blood donors (protocol CRD42014005179 published on PROSPERO).

Upcoming Events


PPI Advice Clinic

Plymouth, ITTC Building (PL6 8BX)

Whatever your query, from finding out more about Patient and Public Involvement to creating a PPI...
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Searching and Review Clinic

The University of Exeter, St Luke's campus, South Cloisters (Room 2.35)

These clinics have been set up to help the PenCLAHRC Evidence Synthesis Team to manage and respond...
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Dr Nick Axford appointed as Associate Professor

21 April 2017

Dr Nick Axford joins PenCLAHRC this week as Associate Professor in Health Services and will...
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Want to stay mentally healthy in older age? Stimulate your brain in early life

20 April 2017

Stimulating the brain by taking on leadership roles at work or staying on in education...
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Job Opportunity - Trial Manager

10 April 2017

The University of Exeter Medical School is seeking a Trial Manager to take a lead...
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Research Projects

Comprehensive Mouth Care and Post-operative Pneumonia (CUPPA)

Theme: Evidence for Policy and Practice

A pilot study to see if comprehensive mouth-care reduces the incidence of post-operative pneumonia in...
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Changing Agendas on Sleep, Treatment and Learning in Epilepsy - A long term condition of children (CASTLE)

Theme: Evidence for Policy and Practice

PenCRU and the Evidence Synthesis Team are working with families, charities and health professionals specialising...
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Research Projects