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I am a Research Fellow in Evidence Synthesis and Test Evaluation within the Institute of Health Research at the University of Exeter Medical School.
I’m particularly interested in how test information is understood. Working alongside Professor Chris Hyde has provided an education in test evaluation and associated knotty issues. Through PenCLAHRC we have a network of highly expert researchers taking collaborative and cross-disciplinary approaches which allows test research to cut across the traditional topical and methods boundaries, working with groups including the Exeter Collaboration for Primary Care (APEx), Clinical Epidemiology, and the Cancer Diagnosis group (DISCO).
Dementia is a topical area with particular challenges for diagnostic testing in an environment where people often initially present to their general practitioner with concerns about their memory or cognitive performance. Investigating how to improve the current situation is the focus of my PhD research, with support from PenCLAHRC and collaboration with a range of other University of Exeter researchers. My principal supervisor is Professor Chris Hyde, and my co-supervisors are Dr Mark Pearson and Dr David Llewellyn.
I am also interested by the practical application of diagnostic test data. I teach part of the Clinical Decision Making course for our undergraduate medical students, and am keen to explore how ‘useable’ diagnostic information is for medics and non-medics, and how this usefulness might be improved. I am interested in the impact of false positive and false negative test results on the people who use this data, e.g. medical practitioners, patients and carers. Tests are used for various reasons such as screening, guiding therapy and predicting how a disease might progress. Prognosis is a developing area, and with Chris Hyde our investigations are also looking at the possible added prognostic value of some diagnostic tests.
At the moment, I am carrying out a doctoral research programme looking at optimizing cognitive assessment in primary care to support a more effective route to dementia diagnosis supported by PenCLAHRC. To find out more, please visit the PhD project page.
I have recently completed a Cochrane review of diagnostic test accuracy investigating Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma-induced coagulopathy in adult trauma patients with bleeding, published in the Cochrane Library and working with the Cochrane Injuries Group and colleagues at the University of Exeter, NIHR, Oxford Biomedical Research Centre, Oxford, John Radcliffe Hospital, NHS Blood & Transplant, Oxford, Churchill Hospital, Oxford Haemophilia & Thrombosis Centre, Oxford and the Royal Centre for Defence Medicine ICT Centre, Department of Military Anaesthesia and Critical Care, Birmingham.
I am also currently working with colleagues at John Radcliffe Hospital, NHS Blood & Transplant, Oxford, and the Department of Public Health and Primary Care, University of Cambridge on a diagnostic test accuracy review of tests of haemoglobin levels in blood donors (protocol CRD42014005179 published on PROSPERO).
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University of Exeter
Areas of expertise
18 October 2017
The Dartington Service Design Lab is entering into a strategic
collaboration with PenCHORD (the Peninsula Collaboration...
02 October 2017
Following his recent appointment as Associate Dean for Research for
Plymouth University Peninsula Schools of...
29 September 2017
Many congratulations to Sebastian Rachuba, who was awarded the
Steve Gallivan prize at the EURO Working...
Theme: Evidence for Policy and Practice
This evaluation (EmMA) provides an independent and qualitative
review of the first iteration of the...
Theme: Mental Health & Dementia
Systematic review evaluating the effectiveness and
cost-effectiveness of interventions aimed at improving the mental